Transcutaneous electrical nerve stimulation may be equally effective as pilocarpine.
Some individuals in the ALTENS group demonstrated lasting response and indicated the possibility to induce salivary gland cells regeneration. Randomized, managed, placebo trials are essential to confirm ALTENS' treatment efficacy for painful, radiation-induced dried out mouth, a debilitating condition for most patients. .. Acupuncture-like TENS may be effective for treating radiation-induced xerostomia Phase III outcomes of Radiation Therapy Oncology Group 0537 indicate that acupuncture-like, transcutaneous electrical nerve stimulation may be equally effective as pilocarpine, the current prescription medication in a tablet, to take care of radiation-induced xerostomia , according to a report published in the June 1, 2015 issue of the International Journal of Radiation Oncology * Biology * Physics , the official scientific journal of the American Culture for Radiation Oncology .All analyses were performed with the use of SAS software, version 8.2. Results Patients From 2010 through October 2011 January, a total of 3195 patients underwent TAVI at 34 hospitals. Completeness of the data was examined against the national data source preserved by the French health care authorities. The median follow-up was 114 days , and follow-up was total for 3188 patients . The mean number of patients who were signed up for each hospital was 94 . The mean age was 82.24 months ; 49 percent of patients were females. Serious aortic stenosis was verified in every full cases, with a mean aortic-valve area of 0.2 cm2 and a mean gradient of 48.5 mm Hg . The mean aortic annulus diameter was 22.2 mm. The mean logistic EuroSCORE was 21.3 percent, and the mean STS score was 14.0 percent. A total of 835 patients had a logistic EuroSCORE of significantly less than 20 percent and an STS score of significantly less than 10 percent but had a coexisting condition that medical procedures was contraindicated, including severe calcification of the aorta , a chest-wall deformity or harm by chest-wall irradiation , or oxygen-dependent respiratory insufficiency or various other coexisting condition not contained in risk scores ; 7.4 percent of sufferers acquired a technical contraindication for extracorporeal circulation, and 15.8 percent opted to undergo TAVI instead of conventional surgery.