Response in Sierra Leone to Ebola Outbreak Saved 40.

To see what difference the global response made about the Ebola epidemic, Kucharski and his team decided to observe how the introduction of a large number of new hospital beds may have helped prevent the spread of the deadly virus. We looked at the impact of beds as this is a measure that may be very easily quantified, Kucharski said. If a case was in cure center, it meant they were not in the grouped community potentially spreading disease. The researchers focused on Sierra Leone because that country maintained relatively good data on disease incidence and bed capacity in different districts as time passes, Kucharski said.This description would be consistent with the presence of mutations associated with idiopathic hypogonadotropic hypogonadism and hypothalamic amenorrhea in individuals who don’t have symptoms. The PROKR2 L173R mutation is apparently an example: it’s been reported in more than a dozen sufferers with idiopathic hypogonadotropic hypogonadism, mostly in the heterozygous state, and in a number of these situations was inherited from an asymptomatic parent.9,31,36,37 To elucidate the genetics of hypothalamic amenorrhea even more completely, it’ll be important to undertake in depth sequencing of the genes connected with idiopathic hypogonadotropic hypogonadism in much larger cohorts of individuals with hypothalamic amenorrhea.