Including metastatic colorectal cancers.

ARI-4175 drug might treat colorectal cancer patients with KRAS mutation When combined with other remedies, the drug cetuximab-which functions by slowing or stopping the development of malignancy cells-has been shown to extend survival using types of tumor, including metastatic colorectal cancers. Sadly, about 40 % of colorectal cancer patients-specifically those who carry a mutated form of a gene known as KRAS-do not react to the drug. Experts at Fox Chase Cancer Center in Philadelphia, however, have already been working on a method to overcome this level of resistance to cetuximab by unleashing a second cetuximab driven mechanism using a novel medication called ARI-4175 cialis generic .