Patients were required to possess at least one of four risk criteria: an age group of at least 60 years, the presence of diabetes mellitus, prior myocardial infarction, or earlier revascularization with either PCI or coronary-artery bypass grafting . Angiography was not necessary for enrollment, but if such an operation was planned, it needed to be performed before randomization. Patients who underwent angiography were required to have proof of heart disease . Major exclusion criteria included a brief history of transient ischemic strike or stroke, CABG or PCI within the prior 30 days, renal failure needing dialysis, and concomitant treatment with an oral anticoagulant. From June 27, 2008, through September 12, 2011, we enrolled 9326 patients at 966 sites in 52 countries.‘These findings, and others enjoy it, are in direct conflict with cannabis’ present plan I status under federal regulation, a classification that does not acknowledge the substance’s clinical efficacy and acceptable safety profile,’ he said. Dr. Jonathann Kuo, an interventional pain management professional at North Shore University Hospital in Manhasset, N.Y., said medical marijuana has the potential to be always a valuable alternative for doctors who specialize in chronic pain management. ‘We frequently find that opioids [such as OxyContin, Percocet, Vicodin] aren’t a good long-term remedy for chronic discomfort,’ Kuo said.